Vs System 2PCG is superficially similar to the original Vs. System collectible card game, but is a completely rebuilt game that takes some inspiration from the original. Combat has been streamlined, the turn structure is different, the resource system has been revamped, and the game is no longer collectible, with cards instead being released in a non-random format. A single box contains a full play-set of all cards.

Each player starts with a Main Character, such as Captain America, Iron Man, or Loki and a deck of 60 cards. During the game, you’ll play resources and recruit Supporting Characters like Falcon, Baby Groot, or Nebula. You’ll organize your formation between your Front and Back Rows, you’ll make solo and team attacks against your enemies in order to stun and KO them. You’ll play Plot Twists to enhance your team or hurt your opponent’s. You’ll play locations and activate your team’s super powers. Your Main Character will earn Experience Points and Level Up to dominate the battlefield. Finally, you’ll KO your opponent’s Main Character (or they’ll KO yours).

Each turn, you’ll go through the following four phases in order. Then, the next player takes a turn.
1. Draw Phase - Draw 2 cards from your deck
2. Recovery Phase - Any stunned characters are recovered and then readied.
3. Build Phase - Play a resource or Location. Then using you total resource points recruit new characters form your hand based on their cost.
4. Main Phase - The longest phase consisting of multiple combats as you attack your opponents characters trying to stun and KO them.

The first issue of the Earth 199999 Arc, Vs System 2PCG: The MCU Battles is also the first Giant-Sized Issue of 2018. It not only creates a new Universe for vs System 2PCG is also introduces two new teams. The MCU Heroes and MCU Villains. This 200 card Giant-Sized Issue is perfect step on point for new players as this comes with a full set of cards with images straight from the movies, counters, and a full color rulebook.